Proviron’s traits and attributes
Proviron (Mesterolone) is a structurally altered DHT hormone having an additional methyl group at the carbon one position. This alteration in structure protects it from hepatic breakdown and allows the hormone to survive oral ingestion. Proviron is one of the only anabolic steroids that carries the added methyl group instead of being C17-alpha-alkylated (C17-aa). However, this steroid’s total bioavailability is far less than that of other C17-aa oral steroids as the methyl group protects it from breakdown. It is a significant reason for its being less popular among many performance-enhancing athletes. Nevertheless, it is not entirely justifiable.
Proviron has an androgenic rating of 30 to 40 and an anabolic rating of 100 to 150. These ratings are derived from and measured against testosterone, having a rating of 100 in both categories. Proviron 25 displays deficient anabolic traits despite having an anabolic rating greater than testosterone. On the other hand, the androgenic rating of Proviron tells a different story. Its androgenic activity appears to be higher than what its structural rating implies.
Benefits and Effects of Proviron
Proviron has some significant traits that define its functionality.
Increases the Amount of Free Testosterone
First, it has a strong binding affinity for Sex-Hormone-Binding-Globulin (SHBG) and appears to be one of the most potent anabolic steroids in this respect. This feature enhances the amount of circulating free testosterone. For the anabolic steroid user, it makes sense. A significant percentage of the anabolic steroids are available in a free state, which helps make the steroids more powerful and potent.
Helps with Estrogen
Moreover, Proviron has the ability to interact with the aromatase enzyme, which is responsible for the conversion of testosterone to estrogen. Proviron binds to the aromatase enzyme, inhibits aromatase activity, and offers protection against the side effects of estrogen. Based on the nature of an individual’s cycle, Proviron takes care of all the anti-estrogen needs of an individual.
Anabolic Steroid Enhancers
Mesterolone also carries a strong binding affinity to the androgen receptor, promoting other steroids’ functionality and enhancing metabolic activity through direct lipolysis. It hardens the muscles and gives an excellent aesthetic finish to the body, much like what fitness models aim for. It can be highly beneficial if a person runs a stack with predominantly wet compounds like Testosterone.
Treatment of Male Infertility
As far as the functionality of Proviron as a fertility medication is concerned, it does not suppress gonadotrophs like other anabolic steroids. It increases sperm production due to its extremely strong androgenicity. It enhances the quality and quantity of sperm produced. However, if taken in extraordinarily excessive amounts, Proviron can suppress gonadotropins and notably suppress sperm production.
Libido Benefits
Usually, anabolic compounds are infamous for causing decreased libido and making a person feel uncomfortable and depressed. However, Proviron benefits you by boosting your libido and giving you a comfortable feeling all the time. It is a DHT derivative. DHT is a male sex hormone that is desirable and popular regarding increased sex drive.
What Are the Dosage and Directions for Using Proviron?
The correct dosage of this hormone depends on your experience with it and your objectives. Most of the time, a physician recommends the dosage according to your needs. However, the following dosage is recommended if not otherwise directed by the physician:
In cases of potency disturbances and declining physical activity, a course of Proviron lasting four to six weeks or an uninterrupted prolonged treatment extending over several months is recommended. The method of treatment can be repeated several times according to the requirements. However, the commonly advised dosage of Proviron is one tablet of 25 mg three times daily at the beginning of the treatment and one tablet of 25 mg once or twice a day as the treatment continues.
Therefore, for the development of secondary male sex characters, the advised dosage of Proviron is one tablet of 25 mg three to four times a day for several months. However, one tablet of 25 mg twice or thrice daily is sufficient as the maintenance dose. In the case of oligozoospermia, one Proviron tablet of 25 mg twice or thrice a day is recommended for a cycle of spermatogenesis. Treatment must be repeated after many weeks if necessary in different conditions.
Side Effects of Proviron
Although it has one of the greatest safety ratings among anabolic steroids, Proviron nevertheless has the potential to cause a variety of adverse effects in some users. Despite the low likelihood of them occurring, the potential adverse effects of Proviron do exist. Regarding the usage of Proviron in females, this steroid is not suggested for use in either a therapeutic or performance capacity. This is the case for a number of reasons. Due to the extremely high rate of virilization, it is strongly advised that women who value their femininity do everything in their power to steer clear of it. The following are some of the categories that can be used to classify the potential adverse effects of Proviron:
Androgenic Impacts
The side effects of Proviron include those of an androgenic nature. These side effects include accelerated hair loss in those people predisposed to male pattern baldness and acne. However, these effects are highly dependent on genetic predispositions. Those who are not genetically prone to male pattern baldness will not lose any hair. Similarly, people who are not sensitive to acne might not have any issues with breakouts.
Cardiovascular Strain
One of the most concerning side effects of Proviron is cardiovascular strain, particularly cholesterol issues. This steroid can negatively affect cholesterol at a higher rate than most anabolic steroids. You are cautioned against using this steroid if you suffer from high cholesterol. Even if you are healthy enough to use, you must be very careful about your intake levels.
Testosterone Suppression
Anabolic-androgenic steroids suppress natural testosterone to some degree. The rate of suppression differs significantly between steroids. In the case of Proviron, the suppression rate is minimal yet inconsequential. According to different studies, a total dosage of 150 mg a day or less should not have a notable effect on natural testosterone production.
However, any increase beyond this point will increase the rate of suppression.
Can a Person Run a Proviron Solo?
The solo cycle of any compound is usually not a good idea because most anabolic compounds are extremely suppressive and are most likely to shut down your test production. However, Proviron is not even half as suppressive as other oral steroids. Therefore, the chances of shutting down endogenous test production with Proviron are close to zero. This does not mean that running a solo Proviron can significantly benefit you. This is a compound that most people consider mild. The only difference you will notice by running it solo is some dryness and increased libido. Stacking it with other steroids will help you gain more from its use.
Administration of Proviron in Conjugation with Other Steroids
If you intend to use anabolic steroids, you will find that Proviron stacks nicely with each and every one of them. During the process of cutting, it will be most useful in combination with anabolic steroids such as Masteron, Winstrol, and Anavar, amongst others. It has a dramatic enhancing effect on the androgenic qualities of these steroids, which helps encourage weight growth and the ripped appearance that is desired. During the part of the cycle known as bulking, it stacks well with any and all anabolic steroids. However, it is difficult to say for certain if you need it or not. Some people just retain it in their possession and reach for it whenever they find that they need it.
Using Proviron Post Cycle Therapy
There is a lot of confusion in bodybuilding regarding using Proviron during post-cycle therapy. If we go back to the old school era when SERMs were not available, and people needed help in this regard, they used Proviron. With the wide availability of ancillary drugs and supplements, Proviron does not need to be used for post-cycle therapy. However, Proviron is not a suppressor as other steroids, yet it is still slightly suppressor. Therefore, using it would be counterproductive in post-cycle treatment. There are several better options available these days compared to Proviron.
Indications
Many medical conditions show the requirement of Proviron. Some of these conditions include:
Declining Physical Activity
Easy fatigability, tiredness, reduced efficiency, weak memory, disturbed libido and potency, depressive moods and irritability are common and much-reported attributes to endogen deficiency in the body. These issues can be overcome, managed or improved by using Proviron tablets.
Hypogonadism
Proviron stimulates the development, growth, and function of androgen-dependent target organs. In the case of prepubertal hypogonadism, it promotes the development of secondary male sex characteristics. In all cases of young patients, full laboratory and clinical investigations are essential before starting the treatment. Proviron tablets can be used in cases where a loss of gonadal function has occurred after puberty as a substitution therapy.
Disturbances in Potency
Proviron overcomes disturbances in a lack of sexual potency as a result of low amounts of the hormone androgen. In cases of decreased power where an androgen shortage is not the major cause, it can also be administered as a supplementary therapy to treat the condition.
What to Consider Before Taking Proviron?
Some medicines are not suitable for use for people who have certain conditions. Sometimes, medication can only be taken under specific circumstances according to a physician’s recommendation. Before you start taking Proviron, your physician must know if you have any medical conditions or problems such as liver or kidney problems, hypertension, epilepsy or migraine, diabetes, cancer, etc. Furthermore, if you are taking any other medication, you must provide details to your doctor. This way, a proper prescription can be made according to a person’s requirement for Proviron.
How to Take Proviron?
Before starting the treatment, you need to read the manufacturer’s printed information leaflet from inside the packet. The booklet provides you with detailed information about Proviron tablets. Take the dosage precisely as prescribed by the doctor. Your physician can reduce the number of daily pills you need to take. The correct dosage will be defined and recommended by a certified physician. You can take Proviron before or after meals. Avoid chewing the tablet, and swallow the whole pill with a drink of water. It is beneficial to take the doses simultaneously each day as it will help you remember to take them. If you forget to take a dose, take it when you remember. Avoid taking two doses at the same time in order to make up for a missed dose.
What to Consider While Taking Proviron?
If you are about to start a new medicine, discuss it with your doctor and inform them that you are already taking Proviron. If you are going to have surgery, it is essential to tell your surgeon or anaesthetist that you are taking this medicine. It may affect other drugs used during surgery or the treatment of other illnesses. If you experience prolonged discomfort or stomach pain, blood in vomit, or yellowing of the skin and eyes during the treatment with Proviron, inform your doctor immediately. Moreover, do not stop taking your medicine or alter the dosage without checking with your doctor. If you stop taking it suddenly or change the dosage, your condition may worsen or have unwanted and desired side effects.
How to Get the Most from Your Treatment?
Regular appointments with the doctor to monitor progress help get the most from the treatment. While you are on Proviron, your doctor will want you to have periodic blood tests and examinations of your breasts and prostate because the therapy may increase the growth rate of some types of cancer. These tests and examinations will assist the doctor in ruling out the possibility of these adverse events. It is quite unlikely that Proviron tablets interact with any medication. However, it is always wise to check with a pharmacist to avoid allergies or side effects. The tablets are not suitable for bodybuilding and increasing muscle. strength in healthy men. Therefore, they should avoid taking steroids for this reason. A person can get the most from the treatment by following these points.
Why Do Doctors Not Recommend Proviron for Female Patients?
Because of its tendency to significantly boost endogenous levels, Proviron is generally not prescribed to female patients. This is the primary reason for this recommendation. On the other hand, it is common knowledge that moderate anabolic steroids are the safest and most effective choice for female users. On the other hand, this does not hold true with the use of Proviron. Because of the powerful androgenic properties of Proviron, it has the potential to cause significant virilization in women, which can include the growth of body hair, the depth of the vocal cords, and the enlargement of the clitoral region. Because of all of these factors, it is strongly advised that females do not use Proviron.
Are There Any Potentially Dangerous Drug Interactions Associated with Proviron?
When combined with immunosuppressant medicines, which lower the immune system, Proviron should be avoided. In addition, it should be avoided when taking medications that are used to treat diabetes; thyroxine, which is used to replace low levels of thyroid hormone; anticoagulants, drugs that are used to treat seizures, and neuromuscular blockers, which are used for the temporary paralysis of skeletal muscles. Because of these interactions, resistance to Proviron can develop, which lowers both its levels and its effectiveness.
Storage
Before it is time to take the medication, make sure the tablets are kept in their pack. If you remove the tablets from their packaging, they might not have a long shelf life. The tablets should be stored in an area that is dry and cold, and the temperature should not exceed 30 degrees Celsius. You shouldn’t keep it or any other medication or steroid anywhere near the sink, on a windowsill, or in the restroom. Make sure that children can’t get their hands on it. You should try to avoid keeping it in the car because the high temperature and the high humidity can make it less effective. Do not flush drugs down the toilet or dispose of them in a sink or drain.
Overdose
Confusion, depression, unconsciousness, dilated pupils, muscle stiffness, disorientation, hypotension, vomiting, heart failure, respiratory depression, and other symptoms may be brought on by an overdose of Proviron. As a result, it is crucial to maintain the dosage that was given to you and to refrain from making any adjustments to it without first consulting a medical professional.
Neglected Dose
It is imperative that each regular dose of this medication be taken in accordance with the directions in order to achieve the greatest possible outcomes. If you forget a dosage, you need to get in touch with your doctor as soon as possible so that you can reorganise your dosing plan. If you forget to take a dose of medication, your doctor may advise you to take it as soon as you realize you forgot. However, it is not advised to take two doses of the medication at the same time in order to make up for the dose that was missed.
